Working at iTeos

Clinical Scientist – CAMBRIDGE, MA (USA)



iTeos Therapeutics is a privately-held, clinical-stage biopharmaceutical company dedicated to extending and improving the lives of cancer patients by designing and developing next generation immunotherapies.
Based in Gosselies, Belgium and Cambridge, MA, iTeos Therapeutics was founded out of the Ludwig Institute for Cancer Research (LICR) and the de Duve Institute (UCLouvain) in 2011.
In March 2020, the Company completed a $125 million Series B2 financing, and in July 2020, we completed our IPO raising over $230million of gross proceeds. In June 2021, iTeos entered into a transformative $2.145 billion co-development and co-commercialization agreement with GSK for EOS-448, iTeos’s anti-TIGIT monoclonal antibody. As a well-capitalized biotech company, iTeos is positioned to continue to develop our pipeline and maintain investment in our discovery research team to leverage our expertise in tumor immunology to improve the lives of cancer patients.
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iTeos Therapeutics is now a world-class biotech in cancer immunotherapy. To carry on its growth, expand its pipeline and reinforce its team, iTeos Therapeutics is looking for a Clinical Scientist

ROLE:  Clinical Scientist

iTeos Therapeutics is searching for a creative, resourceful, integrative thinker Clinical Scientist to translate science and strategy into executable, efficient clinical trials, review emerging clinical data and collaborate on the interpretation and reporting of study results. This position will function under the guidance and direction of the Medical Director. The successful candidate will be an autonomous, proactive, collaborative, experienced scientist with experience working in a clinical development environment. 


  • Contribute to the clinical strategy, including selection of indications and combinations
  • Lead the clinical study protocol/amendment development process by translating the strategy and approved concept into executable, efficient clinical protocols and related documents. 
  • In collaboration with internal/external experts in biostatistics, clinical pharmacology, translational medicine, clinical operations and data management, contribute to the development of the plan to execute trial design including CRF design, laboratory manual review, data review plan, statistical analysis plan review and finalization.
  • Collaborate on the review, analysis, and interpretation of study results and assure appropriate data review and accurate data reporting. 
  • Identify study issues and program issues by reviewing and monitoring emerging clinical data related to safety, efficacy and PK/PD. 
  • Develop sound, strategic solutions to issues and collaborate with the clinical study team to ensure issue resolution. 
  • Conduct literature reviews as needed for study rational, and the interpretation of study data and development of next steps. 
  • Work closely with the medical monitor to ensure he/she is informed of pertinent study information, including but not limited to safety and efficacy data. 
  • Support the development of program documents, including the clinical sections of various regulatory documents such as IND, investigators’ brochures, clinical sections of regulatory submissions, annual reports and updates and clinical study reports to support product approvals. 
  • Work closely with the translational medicine team to support the implementation of target/pathway engagement assays for selecting therapeutically relevant doses and schedules, and potential stratification biomarkers. 
  • Assist with the development of presentations to communicate study data results to colleagues internally and to external audiences including investigators at sponsor meetings or general audiences at scientific conferences. 
  • Maintain current knowledge of the external environment to ensure scientific innovations are considered and/or incorporated into clinical trial development strategy. 
  • Serve as clinical science representative on cross-function teams as assigned.


  • Advanced clinical or science degree (e.g. PharmD, Advanced Practice Nursing, PhD). 
  • 5+ years of clinical, technical/operational experience in planning, executing, reporting and publishing clinical studies within the pharmaceutical industry and/or at clinical sites. 
  • Demonstrated ability to review and summarize study data, including experience in preparing and presenting data.
  • Fluency in English, both written and oral. 
  • Thorough understanding of the drug development process from pre-clinical steps through registration and post-registration required.
  • Broad understanding of functional areas of drug development, including preclinical, regulatory, pharmacovigilance, drug supply, translational medicine, data sciences (data management, biostatistics, programming), and clinical operations (including site selection, study start-up, study conduct, and finalization). 
  • Ability to understand, interpret and communicate clinical information including literature reviews, competitive intelligence, and changing treatment paradigms in order to apply knowledge to support a robust clinical development strategy. 
  • Understanding of trial design and statistics in order to apply knowledge to the design of clinical protocols.
  • Successful track record for the ability to interpret, analyze, and present clinical data, including aggregate data analyses, in order to inform decision-making and set clinical strategy. 
  • Hands-on experience performing systematic literature search, summarizing the search results and presenting the conclusions to wide spectrum of audiences.
  • Strong ability to work effectively in a collaborative team environment where results are achieved through influence, cooperation, and the incorporation of multiple points of view.
  • Strong organization, documentation and communication skills with an ability to multitask. 
  • Excellent interpersonal skills; ability to collaborate across disciplines. 
  • Detailed knowledge of GCP, ICH Guidelines and current EU EMEA and US FDA regulations.
  • Based in Cambridge, MA. Ability to travel up to 10% of time. 


  • Resourceful, energetic, self-starter
  • Approaches challenges with creativity and pragmatism
  • Ability to engage team to achieve goals without direct authority 
  • Driven to move the clinical programs forward at full speed while maintaining quality


  • A stimulating position within a high-potential innovative biotech company
  • The opportunity to work in a science-driven, dynamic, respectful and professional environment
  • A challenging scientific and business growth in which you get to bring your knowledge and skills
  • An employment agreement contract with an attractive salary package in line with the position responsibilities and your experience


Please send your CV together with an adapted cover letter to the following address: Please, mention the reference CS in the message subject. Your application and related information will remain strictly confidential.

For our recruitments in US, we closely collaborate with a Recruitment & Selection company, Planet Pharma. Your application will be automatically forwarded to them. We, together with Planet Pharma, will keep all your data confidential (GDPR compliant approach).

Interested ?

Send your CV together with an adapted cover letter to the following address :
Please mention the reference CS in the mail object.
Your application and related information will remain strictly confidential.